Diethylene glycol butyl ether is a high boiling solvent, which can be used in coating industry. Molecular Weight 134.17 . 111-77-3 - SBASXUCJHJRPEV-UHFFFAOYSA-N - Diethylene glycol monomethyl ether - Similar structures search, synonyms, formulas, resource links, and other chemical information. [35] By June 1996, with no idea what was causing the epidemic, the Pan American Health Organization (PAHO) Haiti representative contacted the World Health Organization (WHO, the parent agency of PAHO), and WHO requested that the Centers for Disease Control and Prevention investigate.[36][29][37]. Common Name. In November, The New York Times published a wine recall that the Federal Government released after the Bureau of Alcohol, Tobacco and Firearms tested 1,000 bottles. Sigma-Aldrich offers a number of Diethylene glycol products. Testing of medication samples taken from the factory samples by both CDC and by an independent commercial lab located in Miami, revealed contamination by DEG of 16.4% and higher. Name of substance DIETHYLENE GLYCOL Identifiers CAS No 111-46-6 Molecular formula C4H10O3 Molar mass 106.1 g/mol SECTION 4: First-aid measures 4.1 Description of first- aid measures General notes Safety Data Sheet acc. Ethylene glycol and diethylene glycol are organic compounds that have applications in the production of coolants for engines. DIETHYLENE GLYCOL MONOBUTYL ETHER is a ether-alcohol derivative. U.S. Federal Regulations TSCA 12(b) Not applicable SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA Occupational Safety and Health Administration Ethylene glycol-TMS, diethylene glycol-TMS, and glycerol-TMS 30 m DB-1 column or 30 m DB-5 column, 60–175° at 4°/min. The agency also identified urinary DEG as a biomarker for DEG exposures. Structure, properties, spectra, suppliers and links for: 2-(2-Ethoxyethoxy)ethanol, 111-90-0, diethylene glycol monoethyl ether. Diethylene glycol structure. diethylene synonyms, diethylene pronunciation, diethylene translation, English dictionary definition of diethylene. Dimethoxyethane, also known as glyme, monoglyme, dimethyl glycol, ethylene glycol dimethyl ether, dimethyl cellosolve, and DME, is a colorless, aprotic, and liquid ether that is used as a solvent, especially in batteries. (Warsaw), 39(2), 1994, 153-159. ass: Standard polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Heat rate: 3 K/min; Start T: 50 C; End T: 230 C; End time: 30 min; CAS no: 111466; Active phase: Supelcowax-10; Carrier gas: He; Phase thickness: 0.25 um; Data type: Linear RI; Authors: Moreira, R.F.A. Availability of DEG will depend on demand for derivatives of the primary product, ethylene glycol, rather than on DEG market requirements."[4]. The product was recalled and after an investigation, the Drug Controller General of India, VG Somani, said at India Pharma 2020, that the GMP was not followed, and negligence was found during the production process itself. It was not until September 1996 that Sinochem provided a name of the manufacturer of the tainted syrup. Glycols related to and coproduced with diethylene glycol and have the formula HOCH2CH2(OCH2CH2)nOH are: 86-13. [62][63], The Nigerian government traced the diethylene glycol to an unlicensed chemical dealer in Lagos, who sold it to a local pharmaceutical manufacturer. As a consequence, the concentrations of the weak acid HEAA and metabolites may cause renal delay, leading to metabolic acidosis and further liver and kidney damage. ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, WARNING: Causes CNS effects, skin, eye, & lung irritation, WARNING: Irritates skin and eyes, harmful if swallowed. Diethylene glycol (DEG) is employed as a comonomer during the synthesis of poly (ethylene terephthalate) (PET). [1] In personal care products (e.g. Global Diethylene Glycol Methyl Ethyl Ethe Market Report to cover Industrial Chain Analysis, Manufacturing Cost Structure, Process Analysis December 17, 2020 6 Min Read Retention indices of amines in some polar and unpolar stationary phases, Latv. Some time later, Wang found a reference to diethylene glycol in a chemical book. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. Diethylene glycol is an organic compound having the chemical formula C 4 H 10 O 3. [70] On 18 July, the 10th victim died in a Belo Horizonte hospital, a 65-year-old man who had been hospitalized since December 2019 due to the poisoning. Synonym: 2-(2-Ethoxyethoxy)ethanol, CARBITOL ™, Diethylene glycol ethyl ether, Diethylene glycol monoethyl ether, Ethyldiglycol Linear Formula: C 2 H 5 OCH … [52], On June 1, 2007, the FDA warned consumers to avoid toothpaste from China, although there was no information if these toothpastes had already entered the US, and started testing any imported Chinese toothpaste. Food Chem., 50, 2002, 7616-7621. ass: Standard polar; Column diameter: 0.32 mm; Column length: 50 m; Column type: Capillary; Heat rate: 2 K/min; Start T: 50 C; End T: 200 C; End time: 40 min; Start time: 5 min; CAS no: 111466; Active phase: Carbowax 20M; Carrier gas: He; Data type: Linear RI; Authors: Chen, C.-C.; Kuo, M.-C.; Liu, S.-E.; Wu, C.-M., Volatile components of salted and pickled prunes (Prunus mume Sieb. 111-90-0 - XXJWXESWEXIICW-UHFFFAOYSA-N - Diethylene glycol monoethyl ether [NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information. Stab., 77, 2002, 55-66. ass: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; CAS no: 111466; Active phase: VF-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Linear RI; Authors: Zheng, Y.; White, E., Retention Data. [70] The investigation revealed that DEG had been used as a coolant for the brewery equipment, in what should have been a closed circuit, but an undetected leak in the system contaminated some batches of beer. Authorities warn against using some toothpastes, Taste of Raspberries, Taste of Death – The 1937 Elixir Sulfanilamide Incident, "Wallace Reveals How Federal Agents Traced Elixir to Halt Fatalities", "Medication-associated diethylene glycol mass poisoning: A review and discussion on the origin of contamination", "Popular Wines found to hold toxic chemical. Polyethylene glycol (PEG; / ˌ p ɒ l i ˈ ɛ θ əl ˌ iː n ˈ ɡ l aɪ ˌ k ɒ l,-ˌ k ɔː l /) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.The structure of PEG is commonly expressed as H−(O−CH 2 −CH 2) n −OH. [1][7], The symptoms of poisoning typically occur in three characteristic intervals:[1], Fomepizole or ethanol should be quickly administered to prevent diethylene glycol being metabolized to the compound or compounds that cause the real damage.[1]. [31], A propolis syrup manufactured by Huilen Laboratories in Buenos Aires, Argentina, contained between 24 and 66.5% DEG, and caused the death of 29 people. Diethylene glycol (DEG) is an organic compound with the formula (HOCH2CH2)2O. [1], DEG is produced by the partial hydrolysis of ethylene oxide. ; Vigdergauz, M.S., Chromatographic constants in gas chromatography (in Russian), Standards Publ. [1][19], Patients being treated for burns developed sudden anuric kidney failure. [3] Because of its adverse effects on humans, diethylene glycol is not allowed for use in food and drugs. Anal. … ; Trugo, L.C. Only 88 children deaths were recalled by doctors or had medical records. Structure of the coordination complex NbCl 3 (dimethoxyethane)(3-hexyne). File; File history; File usage; Global file usage; Size of this PNG preview of this SVG file: 620 × 108 pixels. "Counterfeit Colgate Toothpaste Found", June 14, 2007. The study revealed a strong association between ingestion of two locally produced acetaminophen liquid products (Afebril and Valodon) and illness. The toothpaste was labeled as “Manufactured in South Africa” and contained misspellings like "isclinically", "SOUTH AFRLCA" and "South African Dental Assoxiation". 13533-05-6 - RWXMAAYKJDQVTF-UHFFFAOYSA-N - Diethylene glycol monoacrylate - Similar structures search, synonyms, formulas, resource links, and other chemical information. This value indicates that diethylene glycol bis (methacrylate) will be essentially nonvolatile from water surfaces (2,SRC). Doctors prescribed glycerine for its osmotic diuretic effect, but patients started to develop kidney failure. Nearly half of the victims were under the age of two. [38], Ending June 1996, the FDA had discovered counterfeit glycerin traced back to Chemical Trading and Consulting (a German broker), which bought 72 barrels of the syrup from Vos B.V., a Dutch company. [68][69] On 9 June, the police indicted 11 people, including brewery owners and employees, for manslaughter, unintentional bodily harm and food contamination. [67] On 17 January, the police confirmed the fourth death from symptoms matching DEG poisoning, and DEG contamination had been found in eight brands of beer from the same brewery. Patients were treated with fluid hydration and correction of acidosis, but some were not able to survive. [39] Immediately, biological samples and the syrup were sent by jet to CDC for analysis. 111466. diethylene glycol . Filing a criminal case against the company tested the new product, sulfanilamide. 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